Vacara is a Swedish company dedicated for developing novel diagostic kits, innovative preventions and therapeutics against rheumatoid arthritis.
With physiological expression of human MHC II DRB1 alleles for preclinical studies
"We have used the Cab4 antibody cocktail to establish rheumatoid arthritis in mice for years in defferent mouse strains including BQ, C57BL/6N and Balb/c, both males and females; this cocktail can stably mimic human arthritis for developing a transient joint inflammation, with a fast-starting but long-lasting pain-like behavior."
- Research group from
Karolinska Institutet, Sweden
“We have used the Cab3 cocktail in mice with a C57BL/6J background and the cocktail performed better than expected. Higher incidence and even higher score although using a lower amount of antibody. Although not used extensively, we are overall happy with the cocktail and the results obtained in a traditionally resistant strain to collagen antibody induced arthritis (CAIA).”
- Dr. Bruno Raposo
Karolinska Institutet, Sweden
